We investigate the strategic decision behavior of female entrepreneurs in a realistic market entry experiment where individuals started with gains or losses experienced prior to the game. We compare the entry behavior of female entrepreneurs to the entry behavior of male entrepreneurs and to the entry behavior of female and male students. We find that female entrepreneurs show entry patterns very similar to that of male entrepreneurs and very different from female students: female entrepreneurs on average over enter markets and do not react to their opponents’ prior experiences much. The same accounts for male entrepreneurs. Furthermore, we find that entrepreneurs in general exhibit significantly higher mean entry probabilities than students, whereby students mean entry rate is close to the mixed strategy equilibrium.