Three regulatory options to authorize the use of proteolytic enzymes to tenderize the meat of livestock, except beef which is already approved, and poultry were assessed. The options are: (1) restricting use to beef, (2) restricting use to beef and the meat of all other mature animals and (3) unrestricted use. The analysis focused on the impact upon the supply of tender meat, prices for mature animals, and extent of use of the tenderizers.