This study uses Information Resources, Inc., Household Panel dataset of comprehensive grocery purchase records to investigate relationships among store formats, household demographics, and the healthfulness of grocery purchases. The findings demonstrate that U.S. consumers increasingly shop at nontraditional store formats for their groceries, including supercenters and dollar stores (and other smaller formats), and discuss some possible implications of these changing patterns. Grocery purchases vary considerably, on average, across store formats. Households purchase the most healthful foods at supermarkets and club stores and the least healthful foods at drug stores, convenience stores, and dollar stores. In most cases, the strongest associations with respect to formats and food choices are found for low-income households.