The principles and methods of regional land consolidation in Yunnan Province are expounded. On the basis of differences in topography, climate, soil, hydrology and other natural conditions and the characteristics of spatial layout of land use, agricultural zoning, cropping system and land consolidation measures, the land consolidation zoning indicator system composed of five indicators covering ecological environment, socio-economy, land use, land consolidation and land quality is established by using the GIS spatial analysis and mathematical analysis. Against this backdrop, the Yunnan Province is divided into five first-level land consolidation zones, including the middle-mountain lake basin plateau consolidation zone in central Yunnan, the middle and low mountain wide valley basin consolidation zone in southwest Yunnan, the karst middle and low mountains consolidation zone in southeast Yunnan, the high-mountain and highlands consolidation zone in northeast Yunnan, the middle-mountain and mountain plateau consolidation zone in northeast Yunnan.