A highly disaggregated emissions factor model is presented. The model generates changes in emissions and resource use by state and 6-digit NAICS sector. Removal of all U.S. import restrictions is examined. Results for agriculture show that composition effects explain highly varied regional patterns of emission changes. Scale effects are also important for expanding sectors. Quantitative assessments such as this may prove useful in conducting full environmental reviews of U.S. trade agreements consistent with Executive Order 13141 and the Free Trade Act of 2002.